Novel acyclic enediynes inhibit Cyclin A and Cdc25C expression and induce apoptosis phenomenon to show potent antitumor proliferation. [electronic resource]
Producer: 20070813Description: 4528-36 p. digitalISSN:- 0968-0896
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Blotting, Western
- Caspase Inhibitors
- Caspases -- metabolism
- Cell Cycle -- drug effects
- Cell Cycle Proteins -- antagonists & inhibitors
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cyclin A -- antagonists & inhibitors
- Humans
- Indicators and Reagents
- Quantitative Structure-Activity Relationship
- Signal Transduction -- drug effects
- Structure-Activity Relationship
- cdc25 Phosphatases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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