Oncogenic activation of the PI3-kinase p110β isoform via the tumor-derived PIK3Cβ(D1067V) kinase domain mutation. [electronic resource]
Producer: 20160801Description: 1198-205 p. digitalISSN:- 1476-5594
- Animals
- Carcinoma, Non-Small-Cell Lung -- genetics
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Transformation, Neoplastic -- genetics
- Class I Phosphatidylinositol 3-Kinases
- Humans
- Mice
- Morpholines -- administration & dosage
- Mutation
- NIH 3T3 Cells
- PTEN Phosphohydrolase -- genetics
- Phosphatidylinositol 3-Kinases -- biosynthesis
- Protein Isoforms
- Pyrimidinones -- administration & dosage
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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