Increased expression and activity of RhoA are associated with increased DNA synthesis and reduced p27(Kip1) expression in the vasculature of hypertensive rats. [electronic resource]
Producer: 20011011Description: 488-95 p. digitalISSN:- 1524-4571
- Androstadienes -- pharmacology
- Animals
- Aorta -- drug effects
- Arteries -- drug effects
- Blood Vessels -- drug effects
- Blotting, Western
- Cell Cycle Proteins -- biosynthesis
- Cells, Cultured
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclin-Dependent Kinase Inhibitor p27
- Cyclins -- drug effects
- DNA -- biosynthesis
- Hypertension -- metabolism
- Male
- Muscle, Smooth, Vascular -- cytology
- NG-Nitroarginine Methyl Ester -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Rats
- Rats, Inbred SHR
- Rats, Inbred WKY
- Rats, Sprague-Dawley
- Species Specificity
- Tail -- blood supply
- Thrombin -- pharmacology
- Tumor Suppressor Proteins
- Wortmannin
- rhoA GTP-Binding Protein -- biosynthesis
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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