[6]-Gingerol, from Zingiber officinale, potentiates GLP-1 mediated glucose-stimulated insulin secretion pathway in pancreatic β-cells and increases RAB8/RAB10-regulated membrane presentation of GLUT4 transporters in skeletal muscle to improve hyperglycemia in Lepr [electronic resource]
Producer: 20170901Description: 395 p. digitalISSN:- 1472-6882
- Animals
- Blood Glucose -- metabolism
- Catechols -- pharmacology
- Diabetes Mellitus, Type 2 -- blood
- Fatty Alcohols -- pharmacology
- Zingiber officinale -- chemistry
- Glucagon-Like Peptide 1 -- blood
- Glucose Transporter Type 4 -- metabolism
- Glycogen -- metabolism
- Glycogen Synthase -- metabolism
- Hyperglycemia -- drug therapy
- Insulin -- metabolism
- Insulin Secretion
- Insulin-Secreting Cells -- drug effects
- Membrane Proteins -- metabolism
- Mice
- Mice, Inbred NOD
- Mice, Knockout
- Muscle, Skeletal -- drug effects
- Phytotherapy
- Plant Extracts -- pharmacology
- Secretory Pathway -- drug effects
- Vesicular Transport Proteins -- metabolism
- rab GTP-Binding Proteins -- metabolism
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Publication Type: Journal Article
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