Pharmacokinetic-Pharmacodynamic-Efficacy Modeling of ONO-7579, a Novel Pan-Tropomyosin Receptor Kinase Inhibitor, in a Murine Xenograft Tumor Model. [electronic resource]
Producer: 20200910Description: 361-369 p. digitalISSN:- 1521-0103
- Animals
- Antineoplastic Agents -- pharmacokinetics
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Colorectal Neoplasms -- drug therapy
- Disease Models, Animal
- Female
- Heterografts -- drug effects
- Humans
- Mice
- Mice, Inbred BALB C
- Organic Chemicals -- pharmacokinetics
- Phosphorylation -- drug effects
- Protein Kinase Inhibitors -- pharmacokinetics
- Receptor Protein-Tyrosine Kinases -- antagonists & inhibitors
- Xenograft Model Antitumor Assays -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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