Mevastatin, an inhibitor of HMG-CoA reductase, induces apoptosis, differentiation and Rap1 expression in HL-60 cells. [electronic resource]
Producer: 20030516Description: 1-15 p. digitalISSN:- 0748-6642
- Apoptosis -- drug effects
- Caspase 1 -- metabolism
- Caspase 3
- Caspases -- metabolism
- Cell Differentiation -- drug effects
- Cytochrome c Group -- metabolism
- Dose-Response Relationship, Drug
- Enzyme Activation
- HL-60 Cells -- cytology
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- administration & dosage
- Lovastatin -- administration & dosage
- Membrane Potentials -- drug effects
- Mitochondria -- drug effects
- Reproducibility of Results
- Sensitivity and Specificity
- rap1 GTP-Binding Proteins -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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