Loss of transcriptional activation of the potassium channel Kir5.1 by HNF1β drives autosomal dominant tubulointerstitial kidney disease. [electronic resource]
Producer: 20180612Description: 1145-1156 p. digitalISSN:- 1523-1755
- Animals
- Binding Sites -- genetics
- Chromatin Immunoprecipitation
- Down-Regulation
- HEK293 Cells
- Hepatocyte Nuclear Factor 1-beta -- genetics
- High-Throughput Nucleotide Sequencing
- Humans
- Hypokalemia -- blood
- Kidney -- metabolism
- Magnesium -- blood
- Mice
- Mice, Knockout
- Mutation
- Nephritis, Interstitial -- genetics
- Phenotype
- Potassium -- blood
- Potassium Channels, Inwardly Rectifying -- genetics
- Promoter Regions, Genetic -- genetics
- Transcriptional Activation -- genetics
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Publication Type: Journal Article
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