mTOR kinase inhibition reduces tissue factor expression and growth of pancreatic neuroendocrine tumors. [electronic resource]
Producer: 20200413Description: 169-182 p. digitalISSN:- 1538-7836
- Animals
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Humans
- Mechanistic Target of Rapamycin Complex 1 -- metabolism
- Mechanistic Target of Rapamycin Complex 2 -- metabolism
- Mice, Nude
- Neuroendocrine Tumors -- drug therapy
- Pancreatic Neoplasms -- drug therapy
- Promoter Regions, Genetic
- Protein Kinase Inhibitors -- pharmacology
- Pyrazoles -- pharmacology
- Pyrimidines -- pharmacology
- Signal Transduction
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- Thromboplastin -- genetics
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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