Regulation of expression of BIK proapoptotic protein in human breast cancer cells: p53-dependent induction of BIK mRNA by fulvestrant and proteasomal degradation of BIK protein. [electronic resource]
Producer: 20061204Description: 10153-61 p. digitalISSN:- 0008-5472
- Antineoplastic Agents -- pharmacology
- Antineoplastic Agents, Hormonal -- pharmacology
- Apoptosis Regulatory Proteins -- biosynthesis
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Doxorubicin -- pharmacology
- Estradiol -- analogs & derivatives
- Fulvestrant
- Gamma Rays
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Leupeptins -- pharmacology
- Membrane Proteins -- biosynthesis
- Mitochondrial Proteins
- Promoter Regions, Genetic
- Proteasome Endopeptidase Complex -- metabolism
- Proteasome Inhibitors
- RNA, Messenger -- biosynthesis
- Receptors, Estrogen -- biosynthesis
- Transcription, Genetic -- drug effects
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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