Hydroxyl radical-induced acute diastolic dysfunction is due to calcium overload via reverse-mode Na(+)-Ca(2+) exchange. [electronic resource]
Producer: 20020528Description: 988-95 p. digitalISSN:- 1524-4571
- Actin Cytoskeleton -- drug effects
- Animals
- Calcium -- metabolism
- Calcium Channels, L-Type -- physiology
- Diastole -- drug effects
- Dose-Response Relationship, Drug
- Female
- Heart Ventricles -- drug effects
- Hydroxyl Radical -- pharmacology
- In Vitro Techniques
- Male
- Microscopy, Electron
- Myocardial Contraction -- drug effects
- Myocardium -- metabolism
- Rabbits
- Rats
- Rats, Wistar
- Sarcoplasmic Reticulum -- physiology
- Sodium-Calcium Exchanger -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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