Polyphenolics from mango (Mangifera indica L.) suppress breast cancer ductal carcinoma in situ proliferation through activation of AMPK pathway and suppression of mTOR in athymic nude mice. [electronic resource]
Producer: 20171222Description: 12-19 p. digitalISSN:- 1873-4847
- AMP-Activated Protein Kinases -- antagonists & inhibitors
- Animals
- Antineoplastic Agents, Phytogenic -- analysis
- Breast Neoplasms -- diet therapy
- Carcinoma, Intraductal, Noninfiltrating -- diet therapy
- Cell Line, Tumor
- Cell Proliferation
- Dietary Supplements -- analysis
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Mangifera
- Mice, Nude
- Phosphorylation
- Plant Extracts -- adverse effects
- Polyphenols -- adverse effects
- Protein Processing, Post-Translational
- Pyrogallol -- adverse effects
- RNA Interference
- Reactive Oxygen Species -- agonists
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- Tumor Burden
- Xenograft Model Antitumor Assays
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Publication Type: Comparative Study; Journal Article
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