Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression. [electronic resource]
Producer: 20030530Description: 372-83 p. digitalISSN:- 0026-2862
- Basic Helix-Loop-Helix Transcription Factors
- Cell Division
- Cell Movement
- Cells, Cultured
- Down-Regulation
- Drosophila Proteins
- Endothelium -- cytology
- Endothelium, Vascular -- cytology
- Humans
- Insect Proteins -- metabolism
- Membrane Proteins -- metabolism
- Neovascularization, Pathologic
- Phenotype
- Plasmids -- metabolism
- Proto-Oncogene Proteins -- biosynthesis
- Receptor, Notch4
- Receptors, Cell Surface
- Receptors, Notch
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- Time Factors
- Transcription Factors
- Transfection
- Umbilical Veins -- metabolism
- Vascular Endothelial Growth Factor Receptor-2 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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