A novel mechanism for human K2P2.1 channel gating. Facilitation of C-type gating by protonation of extracellular histidine residues. [electronic resource]
Producer: 20080828Description: 19448-55 p. digitalISSN:- 0021-9258
- Animals
- Depression -- genetics
- Female
- Gene Expression Regulation
- Histidine -- chemistry
- Humans
- Hydrogen Bonding
- Hydrogen-Ion Concentration
- Ion Channel Gating
- Organ Specificity
- Pain -- genetics
- Potassium Channels, Tandem Pore Domain -- chemistry
- Protein Structure, Secondary -- genetics
- Protons
- Xenopus laevis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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