Intratumoral injection of interleukin-12 plasmid DNA, either naked or in complex with cationic lipid, results in similar tumor regression in a murine model. [electronic resource]
Producer: 20030415Description: 949-57 p. digitalISSN:- 1535-7163
- Animals
- CD4 Antigens -- biosynthesis
- CD8 Antigens -- biosynthesis
- Cations
- Cytokines -- biosynthesis
- DNA -- metabolism
- DNA, Complementary -- metabolism
- Gene Transfer Techniques
- Genetic Therapy
- Genetic Vectors
- Interferon-gamma -- metabolism
- Interleukin-12 -- administration & dosage
- Kinetics
- Lipid Metabolism
- Lymphatic Diseases
- Mice
- Mice, Inbred BALB C
- Neoplasms -- therapy
- Phenotype
- Plasmids -- metabolism
- Spleen -- cytology
- Splenomegaly
- Time Factors
- Transgenes
- Tumor Cells, Cultured
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Publication Type: Journal Article
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