Radiation and anticancer drugs can facilitate mitochondrial bypass by CD95/Fas via c-FLIP downregulation. [electronic resource]
Producer: 20100709Description: 551-61 p. digitalISSN:- 1476-5403
- Antineoplastic Agents -- pharmacology
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- CASP8 and FADD-Like Apoptosis Regulating Protein -- genetics
- Cell Line, Tumor -- drug effects
- Clinical Trials, Phase I as Topic
- Down-Regulation
- Etoposide -- pharmacology
- Fas Ligand Protein -- genetics
- Humans
- JNK Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Mitochondria -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- RNA Interference
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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