Results
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1.
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Modifications of C-2 on the pyrroloquinoline template aimed at the development of potent herpesvirus antivirals with improved aqueous solubility. [electronic resource] by
- Nieman, James A
- Nair, Sajiv K
- Heasley, Steven E
- Schultz, Brenda L
- Zerth, Herbert M
- Nugent, Richard A
- Chen, Ke
- Stephanski, Kevin J
- Hopkins, Todd A
- Knechtel, Mary L
- Oien, Nancee L
- Wieber, Janet L
- Wathen, Michael W
Producer: 20100802
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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2.
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Acidic triazoles as soluble guanylate cyclase stimulators. [electronic resource] by
- Roberts, Lee R
- Bradley, Paul A
- Bunnage, Mark E
- England, Katherine S
- Fairman, David
- Fobian, Yvette M
- Fox, David N A
- Gymer, Geoff E
- Heasley, Steven E
- Molette, Jerome
- Smith, Graham L
- Schmidt, Michelle A
- Tones, Michael A
- Dack, Kevin N
Producer: 20120131
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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3.
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Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation. [electronic resource] by
- Arhancet, Graciela B
- Walker, Daniel P
- Metz, Sue
- Fobian, Yvette M
- Heasley, Steven E
- Carter, Jeffrey S
- Springer, John R
- Jones, Darin E
- Hayes, Michael J
- Shaffer, Alexander F
- Jerome, Gina M
- Baratta, Michael T
- Zweifel, Ben
- Moore, William M
- Masferrer, Jaime L
- Vazquez, Michael L
Producer: 20131031
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
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4.
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Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: use of a conformation-based hypothesis to facilitate compound design. [electronic resource] by
- Walker, Daniel P
- Arhancet, Graciela B
- Lu, Hwang-Fun
- Heasley, Steven E
- Metz, Sue
- Kablaoui, Natasha M
- Franco, Francisco M
- Hanau, Cathleen E
- Scholten, Jeffrey A
- Springer, John R
- Fobian, Yvette M
- Carter, Jeffrey S
- Xing, Li
- Yang, Shengtian
- Shaffer, Alexander F
- Jerome, Gina M
- Baratta, Michael T
- Moore, William M
- Vazquez, Michael L
Producer: 20131031
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
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5.
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Design, synthesis, and biological evaluation of 3-[4-(2-hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one, a potent, orally active, brain penetrant inhibitor of phosphodiesterase 5 (PDE5). [electronic resource] by
- Hughes, Robert O
- Rogier, D Joseph
- Jacobsen, E Jon
- Walker, John K
- Macinnes, Alan
- Bond, Brian R
- Zhang, Lena L
- Yu, Ying
- Zheng, Yi
- Rumsey, Jeanne M
- Walgren, Jennie L
- Curtiss, Sandra W
- Fobian, Yvette M
- Heasley, Steven E
- Cubbage, Jerry W
- Moon, Joseph B
- Brown, David L
- Acker, Brad A
- Maddux, Todd M
- Tollefson, Mike B
- Mischke, Brent V
- Owen, Dafydd R
- Freskos, John N
- Molyneaux, John M
- Benson, Alan G
- Blevis-Bal, Rhadika M
Producer: 20100504
In:
Journal of medicinal chemistry vol. 53
Availability: No items available.
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6.
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Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases. [electronic resource] by
- Vazquez, Michael L
- Kaila, Neelu
- Strohbach, Joseph W
- Trzupek, John D
- Brown, Matthew F
- Flanagan, Mark E
- Mitton-Fry, Mark J
- Johnson, Timothy A
- TenBrink, Ruth E
- Arnold, Eric P
- Basak, Arindrajit
- Heasley, Steven E
- Kwon, Soojin
- Langille, Jonathan
- Parikh, Mihir D
- Griffin, Sarah H
- Casavant, Jeffrey M
- Duclos, Brian A
- Fenwick, Ashley E
- Harris, Thomas M
- Han, Seungil
- Caspers, Nicole
- Dowty, Martin E
- Yang, Xin
- Banker, Mary Ellen
- Hegen, Martin
- Symanowicz, Peter T
- Li, Li
- Wang, Lu
- Lin, Tsung H
- Jussif, Jason
- Clark, James D
- Telliez, Jean-Baptiste
- Robinson, Ralph P
- Unwalla, Ray
Producer: 20190218
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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7.
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Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist. [electronic resource] by
- Schnute, Mark E
- Wennerstål, Mattias
- Alley, Jennifer
- Bengtsson, Martin
- Blinn, James R
- Bolten, Charles W
- Braden, Timothy
- Bonn, Tomas
- Carlsson, Bo
- Caspers, Nicole
- Chen, Ming
- Choi, Chulho
- Collis, Leon P
- Crouse, Kimberly
- Färnegårdh, Mathias
- Fennell, Kimberly F
- Fish, Susan
- Flick, Andrew C
- Goos-Nilsson, Annika
- Gullberg, Hjalmar
- Harris, Peter K
- Heasley, Steven E
- Hegen, Martin
- Hromockyj, Alexander E
- Hu, Xiao
- Husman, Bolette
- Janosik, Tomasz
- Jones, Peter
- Kaila, Neelu
- Kallin, Elisabet
- Kauppi, Björn
- Kiefer, James R
- Knafels, John
- Koehler, Konrad
- Kruger, Lars
- Kurumbail, Ravi G
- Kyne, Robert E
- Li, Wei
- Löfstedt, Joakim
- Long, Scott A
- Menard, Carol A
- Mente, Scot
- Messing, Dean
- Meyers, Marvin J
- Napierata, Lee
- Nöteberg, Daniel
- Nuhant, Philippe
- Pelc, Matthew J
- Prinsen, Michael J
- Rhönnstad, Patrik
- Backström-Rydin, Eva
- Sandberg, Johnny
- Sandström, Maria
- Shah, Falgun
- Sjöberg, Maria
- Sundell, Aron
- Taylor, Alexandria P
- Thorarensen, Atli
- Trujillo, John I
- Trzupek, John D
- Unwalla, Ray
- Vajdos, Felix F
- Weinberg, Robin A
- Wood, David C
- Xing, Li
- Zamaratski, Edouard
- Zapf, Christoph W
- Zhao, Yajuan
- Wilhelmsson, Anna
- Berstein, Gabriel
Producer: 20190930
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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