GRP78 confers the resistance to 5-FU by activating the c-Src/LSF/TS axis in hepatocellular carcinoma. [electronic resource]
Producer: 20160916Description: 33658-74 p. digitalISSN:- 1949-2553
- Animals
- Antimetabolites, Antineoplastic -- pharmacology
- CSK Tyrosine-Protein Kinase
- Carcinoma, Hepatocellular -- drug therapy
- DNA-Binding Proteins -- metabolism
- Drug Resistance, Neoplasm
- Endoplasmic Reticulum Chaperone BiP
- Female
- Fluorouracil -- pharmacology
- Heat-Shock Proteins -- genetics
- Hep G2 Cells
- Humans
- Liver Neoplasms -- drug therapy
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Middle Aged
- Signal Transduction
- Thymidylate Synthase -- genetics
- Transcription Factors -- metabolism
- Xenograft Model Antitumor Assays
- src-Family Kinases -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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