Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression. [electronic resource]
Producer: 20000914Description: 24500-5 p. digitalISSN:- 0021-9258
- Animals
- Carrier Proteins -- metabolism
- Cell Cycle Proteins
- Cell Death
- Cyclin-Dependent Kinase Inhibitor p27
- Disease Progression
- Enzyme Activation
- Gene Expression Regulation, Neoplastic
- Genes, Tumor Suppressor
- Humans
- Male
- Mice
- Mice, Nude
- Microtubule-Associated Proteins -- genetics
- Prostatic Neoplasms -- genetics
- Protein Serine-Threonine Kinases
- Protein-Tyrosine Kinases -- metabolism
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-akt
- Proto-Oncogenes
- Transcription, Genetic
- Transplantation, Heterologous
- Tumor Cells, Cultured
- Tumor Suppressor Proteins
- bcl-Associated Death Protein
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Publication Type: Journal Article
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