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Exploring aromatic chemical space with NEAT: novel and electronically equivalent aromatic template. [electronic resource] by
- Tu, Meihua
- Rai, Brajesh K
- Mathiowetz, Alan M
- Didiuk, Mary
- Pfefferkorn, Jeffrey A
- Guzman-Perez, Angel
- Benbow, John
- Guimarães, Cristiano R W
- Mente, Scot
- Hayward, Matthew M
- Liras, Spiros
Producer: 20120928
In:
Journal of chemical information and modeling vol. 52
Availability: No items available.
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4.
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Proteome-wide Map of Targets of T790M-EGFR-Directed Covalent Inhibitors. [electronic resource] by
- Niessen, Sherry
- Dix, Melissa M
- Barbas, Sabrina
- Potter, Zachary E
- Lu, Shuyan
- Brodsky, Oleg
- Planken, Simon
- Behenna, Douglas
- Almaden, Chau
- Gajiwala, Ketan S
- Ryan, Kevin
- Ferre, RoseAnn
- Lazear, Michael R
- Hayward, Matthew M
- Kath, John C
- Cravatt, Benjamin F
Producer: 20171226
In:
Cell chemical biology vol. 24
Availability: No items available.
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Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. [electronic resource] by
- Henderson, Jaclyn L
- Kormos, Bethany L
- Hayward, Matthew M
- Coffman, Karen J
- Jasti, Jayasankar
- Kurumbail, Ravi G
- Wager, Travis T
- Verhoest, Patrick R
- Noell, G Stephen
- Chen, Yi
- Needle, Elie
- Berger, Zdenek
- Steyn, Stefanus J
- Houle, Christopher
- Hirst, Warren D
- Galatsis, Paul
Producer: 20150427
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
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A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors. [electronic resource] by
- Lanning, Bryan R
- Whitby, Landon R
- Dix, Melissa M
- Douhan, John
- Gilbert, Adam M
- Hett, Erik C
- Johnson, Theodore O
- Joslyn, Chris
- Kath, John C
- Niessen, Sherry
- Roberts, Lee R
- Schnute, Mark E
- Wang, Chu
- Hulce, Jonathan J
- Wei, Baoxian
- Whiteley, Laurence O
- Hayward, Matthew M
- Cravatt, Benjamin F
Producer: 20141021
In:
Nature chemical biology vol. 10
Availability: No items available.
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Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer. [electronic resource] by
- Bar-Peled, Liron
- Kemper, Esther K
- Suciu, Radu M
- Vinogradova, Ekaterina V
- Backus, Keriann M
- Horning, Benjamin D
- Paul, Thomas A
- Ichu, Taka-Aki
- Svensson, Robert U
- Olucha, Jose
- Chang, Max W
- Kok, Bernard P
- Zhu, Zhou
- Ihle, Nathan T
- Dix, Melissa M
- Jiang, Ping
- Hayward, Matthew M
- Saez, Enrique
- Shaw, Reuben J
- Cravatt, Benjamin F
Producer: 20171101
In:
Cell vol. 171
Availability: No items available.
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8.
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Optimization of a Dicarboxylic Series for in Vivo Inhibition of Citrate Transport by the Solute Carrier 13 (SLC13) Family. [electronic resource] by
- Huard, Kim
- Gosset, James R
- Montgomery, Justin I
- Gilbert, Adam
- Hayward, Matthew M
- Magee, Thomas V
- Cabral, Shawn
- Uccello, Daniel P
- Bahnck, Kevin
- Brown, Janice
- Purkal, Julie
- Gorgoglione, Matthew
- Lanba, Adhiraj
- Futatsugi, Kentaro
- Herr, Michael
- Genung, Nathan E
- Aspnes, Gary
- Polivkova, Jana
- Garcia-Irizarry, Carmen N
- Li, Qifang
- Canterbury, Daniel
- Niosi, Mark
- Vera, Nicholas B
- Li, Zhenhong
- Khunte, Bhagyashree
- Siderewicz, Jaclyn
- Rolph, Timothy
- Erion, Derek M
Producer: 20160712
In:
Journal of medicinal chemistry vol. 59
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Chemical and computational methods for the characterization of covalent reactive groups for the prospective design of irreversible inhibitors. [electronic resource] by
- Flanagan, Mark E
- Abramite, Joseph A
- Anderson, Dennis P
- Aulabaugh, Ann
- Dahal, Upendra P
- Gilbert, Adam M
- Li, Chao
- Montgomery, Justin
- Oppenheimer, Stacey R
- Ryder, Tim
- Schuff, Brandon P
- Uccello, Daniel P
- Walker, Gregory S
- Wu, Yan
- Brown, Matthew F
- Chen, Jinshan M
- Hayward, Matthew M
- Noe, Mark C
- Obach, R Scott
- Philippe, Laurence
- Shanmugasundaram, Veerabahu
- Shapiro, Michael J
- Starr, Jeremy
- Stroh, Justin
- Che, Ye
Producer: 20150226
In:
Journal of medicinal chemistry vol. 57
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10.
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Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia. [electronic resource] by
- Dounay, Amy B
- Anderson, Marie
- Bechle, Bruce M
- Campbell, Brian M
- Claffey, Michelle M
- Evdokimov, Artem
- Evrard, Edelweiss
- Fonseca, Kari R
- Gan, Xinmin
- Ghosh, Somraj
- Hayward, Matthew M
- Horner, Weldon
- Kim, Ji-Young
- McAllister, Laura A
- Pandit, Jayvardhan
- Paradis, Vanessa
- Parikh, Vinod D
- Reese, Matthew R
- Rong, SuoBao
- Salafia, Michelle A
- Schuyten, Katherine
- Strick, Christine A
- Tuttle, Jamison B
- Valentine, James
- Wang, Hong
- Zawadzke, Laura E
- Verhoest, Patrick R
Producer: 20140605
In:
ACS medicinal chemistry letters vol. 3
Availability: No items available.
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Piperazinyl CCR1 antagonists--optimization of human liver microsome stability. [electronic resource] by
- Brown, Matthew F
- Bahnck, Kevin B
- Blumberg, Laura C
- Brissette, William H
- Burrell, Sara A
- Driscoll, James P
- Fedeles, Flavia
- Fisher, Michael B
- Foti, Robert S
- Gladue, Ronald P
- Guzman-Martinez, Aikomari
- Hayward, Matthew M
- Lira, Paul D
- Lillie, Brett M
- Lu, Yi
- Lundquist, Greg D
- McElroy, Eric B
- McGlynn, Molly A
- Paradis, Timothy J
- Poss, Christopher S
- Roache, James H
- Shavnya, Andrei
- Shepard, Richard M
- Trevena, Kristen A
- Tylaska, Laurie A
Producer: 20070807
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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12.
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Delineating the role of cooperativity in the design of potent PROTACs for BTK. [electronic resource] by
- Zorba, Adelajda
- Nguyen, Chuong
- Xu, Yingrong
- Starr, Jeremy
- Borzilleri, Kris
- Smith, James
- Zhu, Hongyao
- Farley, Kathleen A
- Ding, WeiDong
- Schiemer, James
- Feng, Xidong
- Chang, Jeanne S
- Uccello, Daniel P
- Young, Jennifer A
- Garcia-Irrizary, Carmen N
- Czabaniuk, Lara
- Schuff, Brandon
- Oliver, Robert
- Montgomery, Justin
- Hayward, Matthew M
- Coe, Jotham
- Chen, Jinshan
- Niosi, Mark
- Luthra, Suman
- Shah, Jaymin C
- El-Kattan, Ayman
- Qiu, Xiayang
- West, Graham M
- Noe, Mark C
- Shanmugasundaram, Veerabahu
- Gilbert, Adam M
- Brown, Matthew F
- Calabrese, Matthew F
Producer: 20180924
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 115
Availability: No items available.
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13.
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Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841). [electronic resource] by
- Fensome, Andrew
- Ambler, Catherine M
- Arnold, Eric
- Banker, Mary Ellen
- Brown, Matthew F
- Chrencik, Jill
- Clark, James D
- Dowty, Martin E
- Efremov, Ivan V
- Flick, Andrew
- Gerstenberger, Brian S
- Gopalsamy, Ariamala
- Hayward, Matthew M
- Hegen, Martin
- Hollingshead, Brett D
- Jussif, Jason
- Knafels, John D
- Limburg, David C
- Lin, David
- Lin, Tsung H
- Pierce, Betsy S
- Saiah, Eddine
- Sharma, Raman
- Symanowicz, Peter T
- Telliez, Jean-Baptiste
- Trujillo, John I
- Vajdos, Felix F
- Vincent, Fabien
- Wan, Zhao-Kui
- Xing, Li
- Yang, Xiaojing
- Yang, Xin
- Zhang, Liying
Producer: 20191007
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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