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  2. Details for: Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.
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Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells. [electronic resource]

By:
  • Meyers, Robin M
Contributor(s):
  • Bryan, Jordan G
  • McFarland, James M
  • Weir, Barbara A
  • Sizemore, Ann E
  • Xu, Han
  • Dharia, Neekesh V
  • Montgomery, Phillip G
  • Cowley, Glenn S
  • Pantel, Sasha
  • Goodale, Amy
  • Lee, Yenarae
  • Ali, Levi D
  • Jiang, Guozhi
  • Lubonja, Rakela
  • Harrington, William F
  • Strickland, Matthew
  • Wu, Ting
  • Hawes, Derek C
  • Zhivich, Victor A
  • Wyatt, Meghan R
  • Kalani, Zohra
  • Chang, Jaime J
  • Okamoto, Michael
  • Stegmaier, Kimberly
  • Golub, Todd R
  • Boehm, Jesse S
  • Vazquez, Francisca
  • Root, David E
  • Hahn, William C
  • Tsherniak, Aviad
Producer: 20171211Description: 1779-1784 p. digitalISSN:
  • 1546-1718
Subject(s):
  • Algorithms
  • CRISPR-Cas Systems
  • Cell Line, Tumor
  • Computational Biology -- methods
  • DNA Copy Number Variations
  • Gene Dosage -- genetics
  • Genetic Predisposition to Disease -- genetics
  • Humans
  • Models, Genetic
  • Neoplasms -- diagnosis
  • Reproducibility of Results
  • Sensitivity and Specificity
Online resources:
  • Available from publisher's website
In: Nature genetics vol. 49
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Publication Type: Journal Article

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Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.

APA

Meyers R. M., Bryan J. G., McFarland J. M., Weir B. A., Sizemore A. E., Xu H., Dharia N. V., Montgomery P. G., Cowley G. S., Pantel S., Goodale A., Lee Y., Ali L. D., Jiang G., Lubonja R., Harrington W. F., Strickland M., Wu T., Hawes D. C., Zhivich V. A., Wyatt M. R., Kalani Z., Chang J. J., Okamoto M., Stegmaier K., Golub T. R., Boehm J. S., Vazquez F., Root D. E., Hahn W. C. & Tsherniak A. (20171211). Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells. : Nature genetics.

Chicago

Meyers Robin M, Bryan Jordan G, McFarland James M, Weir Barbara A, Sizemore Ann E, Xu Han, Dharia Neekesh V, Montgomery Phillip G, Cowley Glenn S, Pantel Sasha, Goodale Amy, Lee Yenarae, Ali Levi D, Jiang Guozhi, Lubonja Rakela, Harrington William F, Strickland Matthew, Wu Ting, Hawes Derek C, Zhivich Victor A, Wyatt Meghan R, Kalani Zohra, Chang Jaime J, Okamoto Michael, Stegmaier Kimberly, Golub Todd R, Boehm Jesse S, Vazquez Francisca, Root David E, Hahn William C and Tsherniak Aviad. 20171211. Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells. : Nature genetics.

Harvard

Meyers R. M., Bryan J. G., McFarland J. M., Weir B. A., Sizemore A. E., Xu H., Dharia N. V., Montgomery P. G., Cowley G. S., Pantel S., Goodale A., Lee Y., Ali L. D., Jiang G., Lubonja R., Harrington W. F., Strickland M., Wu T., Hawes D. C., Zhivich V. A., Wyatt M. R., Kalani Z., Chang J. J., Okamoto M., Stegmaier K., Golub T. R., Boehm J. S., Vazquez F., Root D. E., Hahn W. C. and Tsherniak A. (20171211). Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells. : Nature genetics.

MLA

Meyers Robin M, Bryan Jordan G, McFarland James M, Weir Barbara A, Sizemore Ann E, Xu Han, Dharia Neekesh V, Montgomery Phillip G, Cowley Glenn S, Pantel Sasha, Goodale Amy, Lee Yenarae, Ali Levi D, Jiang Guozhi, Lubonja Rakela, Harrington William F, Strickland Matthew, Wu Ting, Hawes Derek C, Zhivich Victor A, Wyatt Meghan R, Kalani Zohra, Chang Jaime J, Okamoto Michael, Stegmaier Kimberly, Golub Todd R, Boehm Jesse S, Vazquez Francisca, Root David E, Hahn William C and Tsherniak Aviad. Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells. : Nature genetics. 20171211.

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