Novel N-1 substituted fluoroquinolones inhibit human topoisomerase I activity and exhibit anti-proliferative activity. [electronic resource]
Producer: 20200205Description: 378-383 p. digitalISSN:- 1573-0646
- Animals
- Antineoplastic Agents -- chemistry
- Apoptosis
- Cell Proliferation
- Colonic Neoplasms -- drug therapy
- DNA Topoisomerases, Type I -- chemistry
- Female
- Fluoroquinolones -- chemistry
- Humans
- Mice
- Mice, Nude
- Topoisomerase I Inhibitors -- chemistry
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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