PR-924, a selective inhibitor of the immunoproteasome subunit LMP-7, blocks multiple myeloma cell growth both in vitro and in vivo. [electronic resource]
Producer: 20110207Description: 155-63 p. digitalISSN:- 1365-2141
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Survival -- drug effects
- Drug Evaluation, Preclinical -- methods
- Humans
- Mice
- Mice, SCID
- Multiple Myeloma -- metabolism
- Neoplasm Proteins -- antagonists & inhibitors
- Oligopeptides -- pharmacology
- Plasmacytoma -- drug therapy
- Proteasome Endopeptidase Complex -- metabolism
- Proteasome Inhibitors
- Survival Analysis
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.