RNA interference-mediated FANCF silencing sensitizes OVCAR3 ovarian cancer cells to adriamycin through increased adriamycin-induced apoptosis dependent on JNK activation. [electronic resource]
Producer: 20140305Description: 1721-9 p. digitalISSN:- 1791-2431
- Apoptosis -- drug effects
- BRCA1 Protein -- genetics
- Caspase 3 -- genetics
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Combined Modality Therapy
- Cytochromes c -- genetics
- DNA Damage -- drug effects
- Down-Regulation -- drug effects
- Doxorubicin -- pharmacology
- Fanconi Anemia -- genetics
- Fanconi Anemia Complementation Group F Protein -- genetics
- Female
- Humans
- JNK Mitogen-Activated Protein Kinases -- genetics
- Membrane Potential, Mitochondrial -- drug effects
- Ovarian Neoplasms -- drug therapy
- Poly(ADP-ribose) Polymerases -- genetics
- RNA Interference
- RNA, Small Interfering -- genetics
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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