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In vitro characterization of the antibacterial spectrum of novel bacterial type II topoisomerase inhibitors of the aminobenzimidazole class. [electronic resource] by
- Mani, Nagraj
- Gross, Christian H
- Parsons, Jonathan D
- Hanzelka, Brian
- Müh, Ute
- Mullin, Steve
- Liao, Yusheng
- Grillot, Anne-Laure
- Stamos, Dean
- Charifson, Paul S
- Grossman, Trudy H
Producer: 20060609
In:
Antimicrobial agents and chemotherapy vol. 50
Availability: No items available.
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Phenotypic and structural analyses of hepatitis C virus NS3 protease Arg155 variants: sensitivity to telaprevir (VX-950) and interferon alpha. [electronic resource] by
- Zhou, Yi
- Müh, Ute
- Hanzelka, Brian L
- Bartels, Doug J
- Wei, Yunyi
- Rao, B Govinda
- Brennan, Debra L
- Tigges, Ann M
- Swenson, Lora
- Kwong, Ann D
- Lin, Chao
Producer: 20070913
In:
The Journal of biological chemistry vol. 282
Availability: No items available.
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Phenotypic characterization of resistant Val36 variants of hepatitis C virus NS3-4A serine protease. [electronic resource] by
- Zhou, Yi
- Bartels, Doug J
- Hanzelka, Brian L
- Müh, Ute
- Wei, Yunyi
- Chu, Hui-May
- Tigges, Ann M
- Brennan, Debra L
- Rao, B Govinda
- Swenson, Lora
- Kwong, Ann D
- Lin, Chao
Producer: 20080506
In:
Antimicrobial agents and chemotherapy vol. 52
Availability: No items available.
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Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir. [electronic resource] by
- Sarrazin, Christoph
- Kieffer, Tara L
- Bartels, Doug
- Hanzelka, Brian
- Müh, Ute
- Welker, Martin
- Wincheringer, Dennis
- Zhou, Yi
- Chu, Hui-May
- Lin, Chao
- Weegink, Christine
- Reesink, Henk
- Zeuzem, Stefan
- Kwong, Ann D
Producer: 20070626
In:
Gastroenterology vol. 132
Availability: No items available.
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In vitro phenotypic characterization of hepatitis C virus NS3 protease variants observed in clinical studies of telaprevir. [electronic resource] by
- Jiang, Min
- Mani, Nagraj
- Lin, Chao
- Ardzinski, Andrzej
- Nelson, Michelle
- Reagan, Dugan
- Bartels, Doug
- Zhou, Yi
- Nicolas, Olivier
- Rao, B Govinda
- Müh, Ute
- Hanzelka, Brian
- Tigges, Ann
- Rijnbrand, Rene
- Kieffer, Tara L
Producer: 20140619
In:
Antimicrobial agents and chemotherapy vol. 57
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A novel inhibitor of gyrase B is a potent drug candidate for treatment of tuberculosis and nontuberculosis mycobacterial infections. [electronic resource] by
- Locher, Christopher P
- Jones, Steven M
- Hanzelka, Brian L
- Perola, Emanuele
- Shoen, Carolyn M
- Cynamon, Michael H
- Ngwane, Andile H
- Wiid, Ian J
- van Helden, Paul D
- Betoudji, Fabrice
- Nuermberger, Eric L
- Thomson, John A
Producer: 20151221
In:
Antimicrobial agents and chemotherapy vol. 59
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Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions. [electronic resource] by
- Wang, Tiansheng
- Bemis, Guy
- Hanzelka, Brian
- Zuccola, Harmon
- Wynn, Michael
- Moody, Cameron Stuver
- Green, Jeremy
- Locher, Christopher
- Liu, Aixiang
- Gao, Hongwu
- Xu, Yuzhou
- Wang, Shaohui
- Wang, Jie
- Bennani, Youssef L
- Thomson, John A
- Müh, Ute
Publication details: ACS medicinal chemistry letters Dec 2017
In:
ACS medicinal chemistry letters vol. 8
Availability: No items available.
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10.
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Discovery and Characterization of a Water-Soluble Prodrug of a Dual Inhibitor of Bacterial DNA Gyrase and Topoisomerase IV. [electronic resource] by
- O'Dowd, Hardwin
- Shannon, Dean E
- Chandupatla, Kishan R
- Dixit, Vaishali
- Engtrakul, Juntyma J
- Ye, Zhengqi
- Jones, Steven M
- O'Brien, Colleen F
- Nicolau, David P
- Tessier, Pamela R
- Crandon, Jared L
- Song, Bin
- Macikenas, Dainius
- Hanzelka, Brian L
- Le Tiran, Arnaud
- Bennani, Youssef L
- Charifson, Paul S
- Grillot, Anne-Laure
Producer: 20150720
In:
ACS medicinal chemistry letters vol. 6
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11.
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Second-generation antibacterial benzimidazole ureas: discovery of a preclinical candidate with reduced metabolic liability. [electronic resource] by
- Grillot, Anne-Laure
- Le Tiran, Arnaud
- Shannon, Dean
- Krueger, Elaine
- Liao, Yusheng
- O'Dowd, Hardwin
- Tang, Qing
- Ronkin, Steve
- Wang, Tiansheng
- Waal, Nathan
- Li, Pan
- Lauffer, David
- Sizensky, Emmanuelle
- Tanoury, Jerry
- Perola, Emanuele
- Grossman, Trudy H
- Doyle, Tim
- Hanzelka, Brian
- Jones, Steven
- Dixit, Vaishali
- Ewing, Nigel
- Liao, Shengkai
- Boucher, Brian
- Jacobs, Marc
- Bennani, Youssef
- Charifson, Paul S
Producer: 20150303
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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