Curcumin inhibits telomerase and induces telomere shortening and apoptosis in brain tumour cells. [electronic resource]
Producer: 20140904Description: 1257-70 p. digitalISSN:- 1097-4644
- Antineoplastic Agents, Phytogenic -- metabolism
- Apoptosis -- drug effects
- Brain Neoplasms
- Cell Line, Tumor
- Cell Membrane -- metabolism
- Cell Proliferation -- drug effects
- Cell Shape -- drug effects
- Curcumin -- metabolism
- Cyclin E -- genetics
- DNA Damage
- Down-Regulation -- drug effects
- Drug Screening Assays, Antitumor
- E2F1 Transcription Factor -- genetics
- G2 Phase Cell Cycle Checkpoints
- Gene Expression -- drug effects
- Humans
- Inhibitory Concentration 50
- Oncogene Proteins -- genetics
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Telomerase -- genetics
- Telomere Shortening -- drug effects
- bcl-2-Associated X Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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