Changing the substrate specificity of creatine kinase from creatine to glycocyamine: evidence for a highly evolved active site. [electronic resource]
Producer: 20080304Description: 1519-27 p. digitalISSN:- 0006-3002
- Amino Acid Sequence
- Animals
- Binding Sites
- Creatine -- metabolism
- Creatine Kinase, MM Form -- chemistry
- Evolution, Molecular
- Gene Expression
- Glycine -- analogs & derivatives
- Humans
- Models, Biological
- Models, Molecular
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutant Proteins -- genetics
- Phylogeny
- Rabbits
- Sequence Homology, Amino Acid
- Substrate Specificity
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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