In vivo examination of hydroxyurea and the novel ribonucleotide reductase inhibitors trimidox and didox in combination with the reverse transcriptase inhibitor abacavir: suppression of retrovirus-induced immunodeficiency disease. [electronic resource]
Producer: 20040802Description: 111-20 p. digitalISSN:- 0166-3542
- Animals
- Antiviral Agents -- pharmacology
- Benzamidines -- therapeutic use
- Bone Marrow Cells -- drug effects
- Dideoxynucleosides -- therapeutic use
- Disease Models, Animal
- Drug Therapy, Combination
- Hematopoietic Stem Cells -- drug effects
- Hydroxamic Acids -- therapeutic use
- Hydroxyurea -- adverse effects
- Mice
- Mice, Inbred C57BL
- Murine Acquired Immunodeficiency Syndrome -- blood
- Ribonucleotide Reductases -- antagonists & inhibitors
- Spleen -- pathology
- Splenomegaly
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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