The activation of p38 MAPK primarily contributes to UV-induced RhoB expression by recruiting the c-Jun and p300 to the distal CCAAT box of the RhoB promoter. [electronic resource]
Producer: 20110808Description: 211-6 p. digitalISSN:- 1090-2104
- Activating Transcription Factor 2 -- genetics
- Apoptosis -- genetics
- CCAAT-Binding Factor -- metabolism
- E1A-Associated p300 Protein -- metabolism
- Enzyme Activation
- Gene Expression Regulation
- Humans
- Jurkat Cells
- Promoter Regions, Genetic
- Proto-Oncogene Proteins c-jun -- genetics
- Transcription, Genetic -- radiation effects
- Ultraviolet Rays
- p38 Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- rhoB GTP-Binding Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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