A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells. [electronic resource]
Producer: 20120112Description: 620-34 p. digitalISSN:- 1878-3686
- Cell Transformation, Neoplastic -- metabolism
- Cellular Senescence -- genetics
- Cyclin D1 -- metabolism
- Cyclin D3 -- metabolism
- Cyclin-Dependent Kinase 4 -- metabolism
- Cyclin-Dependent Kinase 6 -- metabolism
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Forkhead Box Protein M1
- Forkhead Transcription Factors -- metabolism
- G1 Phase -- physiology
- HEK293 Cells
- Humans
- Melanocytes -- metabolism
- Melanoma -- metabolism
- Molecular Sequence Data
- Phosphorylation
- Piperazines -- pharmacology
- Proteome
- Pyridines -- pharmacology
- S Phase -- physiology
- Signal Transduction
- Substrate Specificity
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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