Chemical derivatives of a small molecule deubiquitinase inhibitor have antiviral activity against several RNA viruses. [electronic resource]
Producer: 20141230Description: e94491 p. digitalISSN:- 1932-6203
- Animals
- Antiviral Agents -- chemistry
- Cell Line
- Cyanoacrylates
- Encephalomyocarditis virus -- drug effects
- Enzyme Inhibitors -- chemistry
- Host-Pathogen Interactions
- Humans
- La Crosse virus -- drug effects
- Macrophages -- drug effects
- Mice
- Nitriles -- chemistry
- Norovirus -- drug effects
- Norwalk virus -- drug effects
- Primary Cell Culture
- Pyridines -- chemistry
- Sindbis Virus -- drug effects
- Small Molecule Libraries -- chemistry
- Structure-Activity Relationship
- Ubiquitin-Specific Proteases -- antagonists & inhibitors
- Virus Replication -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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