The resistant effect of SIRT1 in oxidative stress-induced senescence of rat nucleus pulposus cell is regulated by Akt-FoxO1 pathway. [electronic resource]
Producer: 20200706ISSN:- 1573-4935
- Animals
- Antioxidants -- pharmacology
- Cell Cycle -- drug effects
- Cellular Senescence -- drug effects
- Chondrocytes -- cytology
- Gene Expression Regulation
- Heterocyclic Compounds, 4 or More Rings -- pharmacology
- Hydrogen Peroxide -- antagonists & inhibitors
- Nerve Tissue Proteins -- antagonists & inhibitors
- Nucleus Pulposus -- cytology
- Oxidative Stress
- Primary Cell Culture
- Proto-Oncogene Proteins c-akt -- genetics
- Quinolones -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Resveratrol -- pharmacology
- Signal Transduction
- Sirtuin 1 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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