Combination of PB2 271A and SR polymorphism at positions 590/591 is critical for viral replication and virulence of swine influenza virus in cultured cells and in vivo. [electronic resource]
Producer: 20120222Description: 1233-7 p. digitalISSN:- 1098-5514
- Animals
- Cell Line
- Humans
- Influenza A Virus, H1N1 Subtype -- genetics
- Influenza, Human -- virology
- Mice
- Mutation
- Orthomyxoviridae Infections -- veterinary
- Polymorphism, Single Nucleotide
- RNA-Dependent RNA Polymerase -- chemistry
- Reassortant Viruses -- genetics
- Swine
- Swine Diseases -- mortality
- Viral Proteins -- chemistry
- Virulence
- Virus Replication
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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