Results
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Design, synthesis and structure-activity relationships of 6-O-arylpropargyl diazalides with potent activity against multidrug-resistant Streptococcus pneumoniae. [electronic resource] by
- Yong, Hong
- Gu, Yu Gui
- Clark, Richard F
- Marron, Thomas
- Ma, Zhenkun
- Soni, Niru
- Stone, Gregory G
- Nilius, Angela M
- Marsh, Kennan
- Djuric, Stevan W
Producer: 20051011
In:
Bioorganic & medicinal chemistry letters vol. 15
Availability: No items available.
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The synthesis and structure-activity relationship studies of selective acetyl-CoA carboxylase inhibitors containing 4-(thiazol-5-yl)but-3-yn-2-amino motif: polar region modifications. [electronic resource] by
- Xu, Xiangdong
- Weitzberg, Moshe
- Keyes, Robert F
- Li, Qun
- Wang, Rongqi
- Wang, Xiaojun
- Zhang, Xiaolin
- Frevert, Ernst U
- Camp, Heidi S
- Beutel, Bruce A
- Sham, Hing L
- Gu, Yu Gui
Producer: 20070529
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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Synthesis and biological evaluation of 6,7-disubstituted 4-aminopyrido[2,3-d]pyrimidines as adenosine kinase inhibitors. [electronic resource] by
- Perner, Richard J
- Lee, Chih-Hung
- Jiang, Meiqun
- Gu, Yu-Gui
- Didomenico, Stanley
- Bayburt, Erol K
- Alexander, Karen M
- Kohlhaas, Kathy L
- Jarvis, Michael F
- Kowaluk, Elizabeth L
- Bhagwat, Shripad S
Producer: 20051031
In:
Bioorganic & medicinal chemistry letters vol. 15
Availability: No items available.
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7.
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5,6,7-trisubstituted 4-aminopyrido[2,3-d]pyrimidines as novel inhibitors of adenosine kinase. [electronic resource] by
- Perner, Richard J
- Gu, Yu-Gui
- Lee, Chih-Hung
- Bayburt, Erol K
- McKie, Jeffery
- Alexander, Karen M
- Kohlhaas, Kathy L
- Wismer, Carol T
- Mikusa, Joe
- Jarvis, Michael F
- Kowaluk, Elizabeth A
- Bhagwat, Shripad S
Producer: 20040105
In:
Journal of medicinal chemistry vol. 46
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8.
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Structure-activity relationships for a novel series of thiazolyl phenyl ether derivatives exhibiting potent and selective acetyl-CoA carboxylase 2 inhibitory activity. [electronic resource] by
- Clark, Richard F
- Zhang, Tianyuan
- Xin, Zhili
- Liu, Gang
- Wang, Ying
- Hansen, T Matthew
- Wang, Xiaojun
- Wang, Rongqi
- Zhang, Xiaolin
- Frevert, Ernst U
- Camp, Heidi S
- Beutel, Bruce A
- Sham, Hing L
- Gu, Yu Gui
Producer: 20070108
In:
Bioorganic & medicinal chemistry letters vol. 16
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9.
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Structure-activity relationships of novel potent MurF inhibitors. [electronic resource] by
- Gu, Yu Gui
- Florjancic, Alan S
- Clark, Richard F
- Zhang, Tianyuan
- Cooper, Curt S
- Anderson, David D
- Lerner, Claude G
- McCall, J Owen
- Cai, Yingna
- Black-Schaefer, Candace L
- Stamper, Geoffrey F
- Hajduk, Philip J
- Beutel, Bruce A
Producer: 20040827
In:
Bioorganic & medicinal chemistry letters vol. 14
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10.
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Gene expression analysis in rats treated with experimental acetyl-coenzyme A carboxylase inhibitors suggests interactions with the peroxisome proliferator-activated receptor alpha pathway. [electronic resource] by
- Waring, Jeffrey F
- Yang, Yi
- Healan-Greenberg, Christine H
- Adler, Andrew L
- Dickinson, Robert
- McNally, Teresa
- Wang, Xiaojun
- Weitzberg, Moshe
- Xu, Xiangdong
- Lisowski, Andrew
- Warder, Scott E
- Gu, Yu Gui
- Zinker, Bradley A
- Blomme, Eric A
- Camp, Heidi S
Producer: 20080219
In:
The Journal of pharmacology and experimental therapeutics vol. 324
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11.
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Synthesis and structure-activity relationships of N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1- methylprop-2-ynyl}carboxy derivatives as selective acetyl-CoA carboxylase 2 inhibitors. [electronic resource] by
- Gu, Yu Gui
- Weitzberg, Moshe
- Clark, Richard F
- Xu, Xiangdong
- Li, Qun
- Zhang, Tianyuan
- Hansen, T Matthew
- Liu, Gang
- Xin, Zhili
- Wang, Xiaojun
- Wang, Rongqi
- McNally, Teresa
- Zinker, Bradley A
- Frevert, Ernst U
- Camp, Heidi S
- Camp, Heidi
- Beutel, Bruce A
- Sham, Hing L
Producer: 20060816
In:
Journal of medicinal chemistry vol. 49
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12.
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Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure. [electronic resource] by
- Longenecker, Kenton L
- Stamper, Geoffrey F
- Hajduk, Philip J
- Fry, Elizabeth H
- Jakob, Clarissa G
- Harlan, John E
- Edalji, Rohinton
- Bartley, Diane M
- Walter, Karl A
- Solomon, Larry R
- Holzman, Thomas F
- Gu, Yu Gui
- Lerner, Claude G
- Beutel, Bruce A
- Stoll, Vincent S
Producer: 20060203
In:
Protein science : a publication of the Protein Society vol. 14
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13.
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Influenza neuraminidase inhibitors: structure-based design of a novel inhibitor series. [electronic resource] by
- Stoll, Vincent
- Stewart, Kent D
- Maring, Clarence J
- Muchmore, Steven
- Giranda, Vincent
- Gu, Yu-gui Y
- Wang, Gary
- Chen, Yuanwei
- Sun, Minghua
- Zhao, Chen
- Kennedy, April L
- Madigan, Darold L
- Xu, Yibo
- Saldivar, Ayda
- Kati, Warren
- Laver, Graeme
- Sowin, Thomas
- Sham, Hing L
- Greer, Jonathan
- Kempf, Dale
Producer: 20030407
In:
Biochemistry vol. 42
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14.
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Structure-based optimization of MurF inhibitors. [electronic resource] by
- Stamper, Geoffrey F
- Longenecker, Kenton L
- Fry, Elizabeth H
- Jakob, Clarissa G
- Florjancic, Alan S
- Gu, Yu-Gui
- Anderson, David D
- Cooper, Curt S
- Zhang, Tianyuan
- Clark, Richard F
- Cia, Yingna
- Black-Schaefer, Candace L
- Owen McCall, J
- Lerner, Claude G
- Hajduk, Philip J
- Beutel, Bruce A
- Stoll, Vincent S
Producer: 20060725
In:
Chemical biology & drug design vol. 67
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15.
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Novel inhibitors of bacterial protein synthesis: structure-activity relationships for 1,8-naphthyridine derivatives incorporating position 3 and 4 variants. [electronic resource] by
- Clark, Richard F
- Wang, Sanyi
- Ma, Zhenkun
- Weitzberg, Moshe
- Motter, Christopher
- Tufano, Michael
- Wagner, Rolf
- Gu, Yu-Gui
- Dandliker, Peter J
- Lerner, Claude G
- Chovan, Linda E
- Cai, Yingna
- Black-Schaefer, Candace L
- Lynch, Linda
- Kalvin, Douglas
- Nilius, Angela M
- Pratt, Steve D
- Soni, Niru
- Zhang, Tianyuan
- Zhang, Xiaolin
- Beutel, Bruce A
Producer: 20050106
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
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16.
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Structure-based characterization and optimization of novel hydrophobic binding interactions in a series of pyrrolidine influenza neuraminidase inhibitors. [electronic resource] by
- Maring, Clarence J
- Stoll, Vincent S
- Zhao, Chen
- Sun, Minghua
- Krueger, Allan C
- Stewart, Kent D
- Madigan, Darold L
- Kati, Warren M
- Xu, Yibo
- Carrick, Robert J
- Montgomery, Debra A
- Kempf-Grote, Anita
- Marsh, Kennan C
- Molla, Akhteruzzaman
- Steffy, Kevin R
- Sham, Hing L
- Laver, W Graeme
- Gu, Yu-gui
- Kempf, Dale J
- Kohlbrenner, William E
Producer: 20050706
In:
Journal of medicinal chemistry vol. 48
Availability: No items available.
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17.
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N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1-methylprop-2-ynyl}carboxy derivatives as acetyl-coA carboxylase inhibitors--improvement of cardiovascular and neurological liabilities via structural modifications. [electronic resource] by
- Gu, Yu Gui
- Weitzberg, Moshe
- Clark, Richard F
- Xu, Xiangdong
- Li, Qun
- Lubbers, Nathan L
- Yang, Yi
- Beno, David W A
- Widomski, Deborah L
- Zhang, Tianyuan
- Hansen, T Matthew
- Keyes, Robert F
- Waring, Jeffrey F
- Carroll, Sherry L
- Wang, Xiaojun
- Wang, Rongqi
- Healan-Greenberg, Christine H
- Blomme, Eric A
- Beutel, Bruce A
- Sham, Hing L
- Camp, Heidi S
Producer: 20070423
In:
Journal of medicinal chemistry vol. 50
Availability: No items available.
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18.
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From bacterial genomes to novel antibacterial agents: discovery, characterization, and antibacterial activity of compounds that bind to HI0065 (YjeE) from Haemophilus influenzae. [electronic resource] by
- Lerner, Claude G
- Hajduk, Philip J
- Wagner, Rolf
- Wagenaar, Frank L
- Woodall, Charlotte
- Gu, Yu-Gui
- Searle, Xenia B
- Florjancic, Alan S
- Zhang, Tianyuan
- Clark, Richard F
- Cooper, Curt S
- Mack, Jamey C
- Yu, Liping
- Cai, Mengli
- Betz, Steven F
- Chovan, Linda E
- McCall, J Owen
- Black-Schaefer, Candace L
- Kakavas, Stephan J
- Schurdak, Mark E
- Comess, Kenneth M
- Walter, Karl A
- Edalji, Rohinton
- Dorwin, Sarah A
- Smith, Richard A
- Hebert, Eric J
- Harlan, John E
- Metzger, Randy E
- Merta, Philip J
- Baranowski, John L
- Coen, Michael L
- Thornewell, Susan J
- Shivakumar, Annapur G
- Saiki, Anne Y
- Soni, Niru
- Bui, Mai
- Balli, Darlene J
- Sanders, William J
- Nilius, Angela M
- Holzman, Thomas F
- Fesik, Stephen W
- Beutel, Bruce A
Producer: 20070905
In:
Chemical biology & drug design vol. 69
Availability: No items available.
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