Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis. [electronic resource]
Producer: 20050225Description: 55137-46 p. digitalISSN:- 0021-9258
- Alanine Transaminase -- blood
- Animals
- Antioxidants -- pharmacology
- Apoptosis
- Blotting, Northern
- Blotting, Western
- Cardiolipins -- metabolism
- Caspase 3
- Caspases -- metabolism
- Catalase -- metabolism
- Cell Survival
- Cells, Cultured
- Cytochromes c -- metabolism
- Diquat -- pharmacology
- Dose-Response Relationship, Drug
- Enzyme Activation
- F2-Isoprostanes -- blood
- Female
- Fibroblasts -- metabolism
- Gene Library
- Glutathione Peroxidase -- biosynthesis
- Herbicides -- pharmacology
- Humans
- Lipid Peroxidation
- Liver -- metabolism
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mitochondria -- metabolism
- Models, Genetic
- Oxidative Stress
- Phospholipid Hydroperoxide Glutathione Peroxidase
- RNA -- metabolism
- RNA, Messenger -- metabolism
- Superoxide Dismutase -- metabolism
- Tissue Distribution
- Transgenes
- tert-Butylhydroperoxide -- pharmacology
- Glutathione Peroxidase GPX1
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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