Identification of plumericin as a potent new inhibitor of the NF-κB pathway with anti-inflammatory activity in vitro and in vivo. [electronic resource]
Producer: 20141112Description: 1676-86 p. digitalISSN:- 1476-5381
- Animals
- Anti-Inflammatory Agents -- pharmacology
- Apocynaceae
- Cell Adhesion Molecules -- metabolism
- Disease Models, Animal
- Dose-Response Relationship, Drug
- HEK293 Cells
- Human Umbilical Vein Endothelial Cells -- drug effects
- Humans
- I-kappa B Kinase -- metabolism
- I-kappa B Proteins -- metabolism
- Indenes -- pharmacology
- Inflammation -- chemically induced
- Inflammation Mediators -- antagonists & inhibitors
- Iridoids -- pharmacology
- Male
- Mice
- Mice, Inbred C57BL
- NF-kappa B -- antagonists & inhibitors
- Phosphorylation
- Plant Extracts -- pharmacology
- Signal Transduction -- drug effects
- Thioglycolates
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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