Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis. [electronic resource]
Producer: 20010614Description: 3961-8 p. digitalISSN:- 0008-5472
- 3',5'-Cyclic-AMP Phosphodiesterases -- antagonists & inhibitors
- 3',5'-Cyclic-GMP Phosphodiesterases -- antagonists & inhibitors
- Animals
- Anticarcinogenic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Division -- drug effects
- Cyclic AMP -- metabolism
- Cyclic GMP -- metabolism
- Cyclic GMP-Dependent Protein Kinases -- metabolism
- Cyclic Nucleotide Phosphodiesterases, Type 4
- Cyclic Nucleotide Phosphodiesterases, Type 5
- Dose-Response Relationship, Drug
- Enzyme Activation -- drug effects
- Female
- Humans
- Inhibitory Concentration 50
- Microscopy, Fluorescence
- Rats
- Rats, Inbred F344
- Sulindac -- analogs & derivatives
- Tumor Cells, Cultured
- Urinary Bladder Neoplasms -- chemically induced
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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