Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice. [electronic resource]
Producer: 20050818Description: 185-98 p. digitalISSN:- 0006-8993
- Amyotrophic Lateral Sclerosis -- enzymology
- Animals
- Apoptosis -- physiology
- Caspase 3
- Caspases -- metabolism
- Disease Models, Animal
- Disease Progression
- Enzyme Activation -- physiology
- Humans
- JNK Mitogen-Activated Protein Kinases -- metabolism
- MAP Kinase Kinase 3
- MAP Kinase Kinase Kinase 5 -- metabolism
- Mice
- Mice, Transgenic
- Motor Cortex -- enzymology
- Motor Neurons -- enzymology
- Mutation -- genetics
- Oxidative Stress -- physiology
- Phosphorylation
- Signal Transduction -- physiology
- Superoxide Dismutase -- genetics
- Superoxide Dismutase-1
- Up-Regulation -- physiology
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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