The molecular function and clinical phenotype of partial deletions of the IGF2/H19 imprinting control region depends on the spatial arrangement of the remaining CTCF-binding sites. [electronic resource]
Producer: 20130701Description: 544-57 p. digitalISSN:- 1460-2083
- Alleles
- Binding Sites -- genetics
- CCCTC-Binding Factor
- Cells, Cultured
- Chromatin Immunoprecipitation
- Chromosomes, Human, Pair 11 -- genetics
- DNA Methylation
- Gene Deletion
- Gene Expression Regulation
- Gene Silencing
- Genetic Loci
- Genomic Imprinting
- Humans
- Insulin-Like Growth Factor II -- genetics
- Pedigree
- Phenotype
- RNA, Long Noncoding -- genetics
- Repressor Proteins -- genetics
- Sequence Analysis, DNA
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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