β-lactam substituted polycyclic fused pyrrolidine/pyrrolizidine derivatives eradicate C. albicans in an ex vivo human dentinal tubule model by inhibiting sterol 14-α demethylase and cAMP pathway. [electronic resource]
Producer: 20160505Description: 636-47 p. digitalISSN:- 0006-3002
- 14-alpha Demethylase Inhibitors -- pharmacology
- Antifungal Agents -- chemistry
- Candida albicans -- growth & development
- Candidiasis -- drug therapy
- Cyclic AMP -- metabolism
- Dental Pulp Cavity -- metabolism
- Humans
- Models, Biological
- Second Messenger Systems
- Sterol 14-Demethylase -- metabolism
- beta-Lactams -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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