Biallelic mutations in p16(INK4a) confer resistance to Ras- and Ets-induced senescence in human diploid fibroblasts. [electronic resource]
Producer: 20030102Description: 8135-43 p. digitalISSN:- 0270-7306
- Adult
- Alleles
- Animals
- Cell Line
- Cellular Senescence -- physiology
- Cyclin-Dependent Kinase 4
- Cyclin-Dependent Kinase Inhibitor p16 -- genetics
- Cyclin-Dependent Kinases -- genetics
- Dermis -- cytology
- Female
- Fibroblasts -- physiology
- Gene Expression Regulation
- Humans
- Male
- Melanoma
- Mutation
- Proto-Oncogene Protein c-ets-1
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-ets
- Transcription Factors -- metabolism
- Tumor Suppressor Protein p14ARF -- genetics
- Tumor Suppressor Protein p53 -- metabolism
- ras Proteins -- metabolism
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Publication Type: Journal Article
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