Small structural changes on a hydroquinone scaffold determine the complex I inhibition or uncoupling of tumoral oxidative phosphorylation. [electronic resource]
Producer: 20160520Description: 46-57 p. digitalISSN:- 1096-0333
- Adenocarcinoma -- metabolism
- Animals
- Cell Line, Tumor
- Dose-Response Relationship, Drug
- Electron Transport Complex I -- antagonists & inhibitors
- Humans
- Hydroquinones -- chemistry
- Male
- Mice
- Mitochondria, Liver -- drug effects
- Oxidative Phosphorylation -- drug effects
- Oxygen Consumption -- drug effects
- Rats
- Uncoupling Agents -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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