DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis. [electronic resource]
Producer: 20170515Description: 46-53 p. digitalISSN:- 1552-4469
- Animals
- Boronic Acids -- chemistry
- Caspase 1 -- deficiency
- Cell Line
- Dipeptidases -- antagonists & inhibitors
- Dipeptides -- chemistry
- Dipeptidyl-Peptidases and Tripeptidyl-Peptidases -- antagonists & inhibitors
- Dose-Response Relationship, Drug
- Humans
- Leukocytes, Mononuclear -- drug effects
- Macrophages -- drug effects
- Mice
- Molecular Conformation
- Pyroptosis -- drug effects
- Serine Proteinase Inhibitors -- chemistry
- Structure-Activity Relationship
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Publication Type: Journal Article
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