The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson's Disease. [electronic resource]
Producer: 20191031Description: 2976-2988 p. digitalISSN:- 2211-1247
- Animals
- Autophagy
- Disease Models, Animal
- Dopaminergic Neurons -- metabolism
- Drosophila melanogaster -- physiology
- Endoplasmic Reticulum Stress
- Glucosylceramidase -- metabolism
- Humans
- Induced Pluripotent Stem Cells -- pathology
- Mitochondria -- metabolism
- Mitochondrial Dynamics
- Motor Activity
- NAD -- metabolism
- Neurons -- metabolism
- Niacinamide -- analogs & derivatives
- Parkinson Disease -- pathology
- Pyridinium Compounds
- Unfolded Protein Response
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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