Synergistic cooperation between ABT-263 and MEK1/2 inhibitor: effect on apoptosis and proliferation of acute myeloid leukemia cells. [electronic resource]
Producer: 20161107Description: 845-59 p. digitalISSN:- 1949-2553
- Acute Disease
- Aniline Compounds -- administration & dosage
- Animals
- Antineoplastic Agents -- administration & dosage
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Drug Synergism
- G1 Phase Cell Cycle Checkpoints -- drug effects
- HL-60 Cells
- Humans
- Immunohistochemistry
- Leukemia, Myeloid -- drug therapy
- MAP Kinase Kinase 1 -- antagonists & inhibitors
- MAP Kinase Kinase 2 -- antagonists & inhibitors
- Mice, Inbred NOD
- Mice, Knockout
- Mice, SCID
- Niacinamide -- administration & dosage
- Protein Kinase Inhibitors -- administration & dosage
- Sulfonamides -- administration & dosage
- Tumor Burden -- drug effects
- U937 Cells
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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