Synthesis and development of new 2-substituted 1-[3-(4-arylpiperazin-1-yl)propyl]-pyrrolidin-2-one derivatives with antiarrhythmic, hypotensive, and alpha-adrenolytic activity. [electronic resource]
Producer: 20060105Description: 793-803 p. digitalISSN:- 0014-827X
- Adrenergic alpha-Agonists -- chemical synthesis
- Animals
- Anti-Arrhythmia Agents -- chemical synthesis
- Antihypertensive Agents -- chemical synthesis
- Arrhythmias, Cardiac -- drug therapy
- Blood Pressure -- drug effects
- Hypertension -- drug therapy
- Male
- Mice
- Molecular Structure
- Pyrrolidines -- chemical synthesis
- Radioligand Assay
- Rats
- Rats, Wistar
- Receptors, Adrenergic, alpha -- metabolism
- Toxicity Tests, Acute
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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