The anti-human leukocyte antigen-DR monoclonal antibody 1D09C3 activates the mitochondrial cell death pathway and exerts a potent antitumor activity in lymphoma-bearing nonobese diabetic/severe combined immunodeficient mice. [electronic resource]
Producer: 20060321Description: 1799-808 p. digitalISSN:- 0008-5472
- Animals
- Antibodies, Monoclonal -- immunology
- Cell Death -- drug effects
- Cell Growth Processes -- drug effects
- Cell Line, Tumor
- Female
- HLA-DR Antigens -- immunology
- Humans
- Leukemia, Lymphocytic, Chronic, B-Cell -- immunology
- Lymphoma, Non-Hodgkin -- immunology
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Mitochondria -- drug effects
- Reactive Oxygen Species -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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