Cellular prion protein inhibits proapoptotic Bax conformational change in human neurons and in breast carcinoma MCF-7 cells. [electronic resource]
Producer: 20050929Description: 783-95 p. digitalISSN:- 1350-9047
- Apoptosis -- drug effects
- BH3 Interacting Domain Death Agonist Protein
- Breast Neoplasms -- metabolism
- Carrier Proteins -- metabolism
- Caspase 6
- Cell Line, Tumor
- Cysteine Endopeptidases -- metabolism
- Cytochromes c -- metabolism
- Enzyme Inhibitors -- pharmacology
- Female
- Humans
- Membrane Proteins -- metabolism
- Mitochondria -- metabolism
- Neurons -- drug effects
- PrPC Proteins -- metabolism
- Protein Structure, Quaternary
- Protein Transport -- drug effects
- Proto-Oncogene Proteins c-bcl-2 -- antagonists & inhibitors
- Thapsigargin -- pharmacology
- bcl-2 Homologous Antagonist-Killer Protein
- bcl-2-Associated X Protein
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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