Levels of prostaglandin E metabolite and leukotriene E(4) are increased in the urine of smokers: evidence that celecoxib shunts arachidonic acid into the 5-lipoxygenase pathway. [electronic resource]
Producer: 20090623Description: 322-9 p. digitalISSN:- 1940-6215
- Arachidonate 5-Lipoxygenase -- drug effects
- Arachidonic Acid -- metabolism
- Celecoxib
- Cyclooxygenase 2 -- metabolism
- Cyclooxygenase 2 Inhibitors -- pharmacology
- Female
- Humans
- Leukotriene E4 -- urine
- Male
- Middle Aged
- Pneumonia -- chemically induced
- Prostaglandins E -- metabolism
- Pyrazoles -- pharmacology
- Signal Transduction
- Smoking -- adverse effects
- Sulfonamides -- pharmacology
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Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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