Differential regulation of human eosinophil IL-3, IL-5, and GM-CSF receptor alpha-chain expression by cytokines: IL-3, IL-5, and GM-CSF down-regulate IL-5 receptor alpha expression with loss of IL-5 responsiveness, but up-regulate IL-3 receptor alpha expression. [electronic resource]
Producer: 20030902Description: 5359-66 p. digitalISSN:- 0022-1767
- Cell Differentiation -- immunology
- Cell Membrane -- immunology
- Cells, Cultured
- Dose-Response Relationship, Immunologic
- Down-Regulation -- immunology
- Eosinophils -- enzymology
- Granulocyte-Macrophage Colony-Stimulating Factor -- physiology
- Humans
- Interleukin-3 -- physiology
- Interleukin-5 -- antagonists & inhibitors
- Phosphatidylinositol 3-Kinases -- physiology
- Protein Subunits -- antagonists & inhibitors
- RNA, Messenger -- antagonists & inhibitors
- Receptors, CCR3
- Receptors, Chemokine -- antagonists & inhibitors
- Receptors, Granulocyte-Macrophage Colony-Stimulating Factor -- antagonists & inhibitors
- Receptors, Interleukin -- antagonists & inhibitors
- Receptors, Interleukin-3 -- biosynthesis
- Receptors, Interleukin-5
- Signal Transduction -- immunology
- Up-Regulation -- immunology
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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