Downregulating Akt/NF-κB signaling and its antioxidant activity with Loureirin A for alleviating the progression of osteoarthritis: In vitro and vivo studies. [electronic resource]
Producer: 20201021Description: 105953 p. digitalISSN:- 1878-1705
- Animals
- Anti-Inflammatory Agents -- pharmacology
- Antioxidants -- pharmacology
- Cell Survival -- drug effects
- Cells, Cultured
- Chalcones -- pharmacology
- Chondrocytes -- drug effects
- Down-Regulation -- drug effects
- Extracellular Matrix -- drug effects
- Female
- Male
- Malondialdehyde -- metabolism
- Mice, Inbred C57BL
- NF-kappa B -- metabolism
- Osteoarthritis -- drug therapy
- Proto-Oncogene Proteins c-akt -- metabolism
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Superoxide Dismutase -- metabolism
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Publication Type: Journal Article
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